Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis- manufacturers
- S26131
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- $36.00
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2026-07-16
- CAS:296280-56-3
- Purity: 99.77%
- Supply Ability: 10g
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| | Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis- Basic information |
| Product Name: | Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis- | | Synonyms: | Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis-;S26131; S 26131; S-26131.;S26131;N-[2-[7-[3-[8-(2-acetamidoethyl)naphthalen-2-yl]oxypropoxy]naphthalen-1-yl]ethyl]acetamide;inhibit,S-26131,S26131,S 26131,melatoninergic,ligand,MT2,antagonist,selectively,Melatonin Receptor,Inhibitor;S26131, 10 mM in DMSO | | CAS: | 296280-56-3 | | MF: | C31H34N2O4 | | MW: | 498.61 | | EINECS: | | | Product Categories: | APIS | | Mol File: | 296280-56-3.mol | ![Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis- Structure](CAS/20200401/GIF/296280-56-3.gif) |
| | Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis- Chemical Properties |
| Melting point | 113-116 °C(Solv: toluene (108-88-3)) | | Boiling point | 804.6±65.0 °C(Predicted) | | density | 1.168±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:5.0(Max Conc. mg/mL);10.03(Max Conc. mM) | | form | Solid | | pka | 15.86±0.46(Predicted) | | color | Off-white to light brown |
| | Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis- Usage And Synthesis |
| Uses | S26131 (compound 5) is a potent and selective MT1 melatoninergic ligand, and the Ki values are 0.5 and 112 nM for MT1 and MT2, respectively. S26131 behaves as an MT1 and MT2 antagonist[1]. | | References | [1] Descamps-Franois C, et al. Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands. J Med Chem. 2003 Mar 27;46(7):1127-9. DOI:10.1021/jm0255872 |
| | Acetamide, N,N'-[1,3-propanediylbis(oxy-7,1-naphthalenediyl-2,1-ethanediyl)]bis- Preparation Products And Raw materials |
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