| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:Rac-VU6008667 CAS:2092917-63-8 Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
Fan De(Beijing) Biotechnology Co., Ltd.
|
| Tel: |
15911056312 |
| Email: |
liming@bio-fount.com |
| Products Intro: |
Product Name:5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- CAS:2092917-63-8 Purity:97.0% Package:5mg
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5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- manufacturers
- (Rac)-VU 6008667
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- $62.00
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2026-05-06
- CAS:2092917-63-8
- Purity: 99.82%
- Supply Ability: 10g
- (Rac)-VU 6008667
-
- $62.00
-
2026-04-21
- CAS:2092917-63-8
- Purity: 99.82%
- Supply Ability: 10g
|
| | 5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- Basic information |
| Product Name: | 5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- | | Synonyms: | 5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro-;(Rac)-VU 6008667;(Rac)VU 6008667,(Rac) VU 6008667 | | CAS: | 2092917-63-8 | | MF: | C24H17ClF2N2O2 | | MW: | 438.85 | | EINECS: | | | Product Categories: | | | Mol File: | 2092917-63-8.mol | ![5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- Structure](CAS/20200401/GIF/2092917-63-8.gif) |
| | 5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- Chemical Properties |
| Boiling point | 616.1±55.0 °C(Predicted) | | density | 1.48±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 125 mg/mL (284.84 mM); Water: < 0.1 mg/mL (insoluble) | | form | Solid | | pka | -2.76±0.40(Predicted) | | color | White to off-white |
| | 5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- Usage And Synthesis |
| Uses | (Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration[1]. | | IC 50 | mAChR5 | | References | [1] McGowan KM et al, Continued optimization of the M5 NAM ML375: Discovery of VU6008667, an M5 NAM with high CNS penetration and a desired short half-life in rat for addiction studies. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359. DOI:10.1016/j.bmcl.2017.02.020 |
| | 5H-Imidazo[2,1-a]isoindol-5-one, 9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-1,2,3,9b-tetrahydro- Preparation Products And Raw materials |
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