| Company Name: |
Shanghai Universal Biotech Co.,Ltd
|
| Tel: |
15921930842 15921930842 |
| Email: |
yh-wang@univ-bio.com |
| Products Intro: |
Product Name:COX IV (4D11-B3-E8) Mouse mAb
Purity:见优宁维官网 Package:100ul/RMB 10
|
| Company Name: |
Cell Signaling Technology Inc
|
| Tel: |
21-80243558 86218024 |
| Email: |
info@cellsignal.cn |
| Products Intro: |
Product Name:COX IV (4D11-B3-E8) Mouse mAb
|
|
| | COX IV (4D11-B3-E8) Mouse mAb Chemical Properties |
| | COX IV (4D11-B3-E8) Mouse mAb Usage And Synthesis |
| Source | Mouse | | Reactivity | Human;Mouse;Rat;Monkey | | Background | Cytochrome c oxidase is a hetero-oligomeric enzyme consisting of 13 subunits localized to the inner mitochondrial membrane. It is the terminal enzyme complex in the respiratory chain, catalyzing the reduction of molecular oxygen to water coupled to the translocation of protons across the mitochondrial inner membrane to drive ATP synthesis. The 3 largest subunits forming the catalytic core are encoded by mitochondrial DNA, while the other smaller subunits, including COX IV, are nuclear-encoded. Research studies have shown that deficiency in COX activity correlates with a number of human diseases. The COX IV antibody can be used effectively as a mitochondrial loading control in cell-based research assays. | | References | [1] Ostermeier, C. et al. (1996) Curr. Opin. Struct. Biol. 6, 460-466.
[2] Capaldi, R.A. et al. (1983) Biochim. Biophys. Acta 726, 135-148.
[3] Kadenbach, B. et al. (2000) Free Radic. Biol. Med. 29, 211-221.
[4] Barrientos, A. et al. (2002) Gene 286, 53-63. |
| | COX IV (4D11-B3-E8) Mouse mAb Preparation Products And Raw materials |
|