| Company Name: |
GL Biochem (Shanghai) Ltd
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| Tel: |
21-61263452 13641803416 |
| Email: |
ymbetter@glbiochem.com |
| Products Intro: |
Product Name:Smac N7 Protein;AVPIAQK
CAS:401913-57-3
Purity:95% HPLC 98% HPLC Package:1mg,5mg,10mg,25mg,100mg,1g,10g
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| Company Name: |
Shanghai Hanhong Scientific Co.,Ltd.
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| Tel: |
021-54306202 13764082696 |
| Email: |
info@hanhongsci.com |
| Products Intro: |
Product Name:Smac-N7 Peptide
CAS:401913-57-3
Remarks:332P1405
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
|
| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:SMac-N7 Peptide;H-Ala-Val-Pro-Ile-Ala-Gln-Lys-OH;Mitochondrial Diablo HoMolog (1-7) (huMan, Mouse), Second Mitochondria-derived Activator of Caspase (1-7) (huMan, Mouse), SMac Protein (1-7) (huMan, Mouse)
CAS:401913-57-3
Purity:99% Package:1.0Mg
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| | H-AVPIAQK-OH Basic information |
| Product Name: | H-AVPIAQK-OH | | Synonyms: | H-AVPIAQK-OH;H-ALA-VAL-PRO-ILE-ALA-GLN-LYS-OH;AVPIAQK;SMAC-N7 PEPTIDE;SMAC N7 PROTEIN;SMAC PROTEIN (1-7) (HUMAN, MOUSE);Mitochondrial Diablo HoMolog (1-7) (huMan, Mouse), Second Mitochondria-derived Activator of Caspase (1-7) (huMan, Mouse), SMac Protein (1-7) (huMan, Mouse);L-Lysine, L-alanyl-L-valyl-L-prolyl-L-isoleucyl-L-alanyl-L-glutaminyl- | | CAS: | 401913-57-3 | | MF: | C33H59N9O9 | | MW: | 725.88 | | EINECS: | | | Product Categories: | peptide | | Mol File: | 401913-57-3.mol |  |
| | H-AVPIAQK-OH Chemical Properties |
| storage temp. | -20°C | | form | lyophilized solid | | color | white | | Water Solubility | water: 1mg/mL
DMSO: 5mg/mL | | Sequence | Ala-Val-Pro-Ile-Ala-Gln-Lys |
| | H-AVPIAQK-OH Usage And Synthesis |
| Uses | Smac-N7 peptide, the seven N-terminal amino acid of the mitochondrial protein Smac (second mitochondria-derived activator of caspase), cannot pass through the cell membrane[1]. | | Biological Activity | Cell permeable: no', 'Kd ~800 nM in binding to the BIR2 and BIR3 (baculovirus IAP repeat) domains of XIAP (X-linked inhibitor of apoptosis proteins)', 'Primary Target
Promotes the catalytic activity of caspase-9 in the presence of XIAP', 'Product does not compete with ATP.', 'Reversible: no | | References | [1] S Heckl, et al. A novel polyarginine containing Smac peptide conjugate that mediates cell death in tumor and healthy cells. Med Chem. 2008 Jul;4(4):348-54. DOI:10.2174/157340608784872217 |
| | H-AVPIAQK-OH Preparation Products And Raw materials |
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