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| | 2,5-Dibromo-4-methylimidazole Basic information |
| | 2,5-Dibromo-4-methylimidazole Chemical Properties |
| Boiling point | 343.1±34.0 °C(Predicted) | | density | 2.188±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 9.47±0.10(Predicted) | | Appearance | Off-white to light yellow Solid |
| | 2,5-Dibromo-4-methylimidazole Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 2,5-dibromo-4-methylimidazole from 4-methylimidazole: 4-methylimidazole (3.4 g, 40 mmol) was dissolved in tetrahydrofuran (THF, 50 mL) at room temperature. Subsequently, N-bromosuccinimide (NBS, 14 g, 80 mmol) was added to this solution. The reaction mixture was stirred for 1 hour. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography (eluent ratio: petroleum ether (PE):ethyl acetate (EA) = 2:1) to afford 2,5-dibromo-4-methylimidazole (9.6 g, 99% yield) as a white solid. Mass spectrometry (ESI-MS) analysis showed: m/z 239.0 [M + H]+. | | References | [1] Patent: WO2015/26792, 2015, A1. Location in patent: Paragraph 0229 |
| | 2,5-Dibromo-4-methylimidazole Preparation Products And Raw materials |
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