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| Product Name: | TC4, HUMAN | | Synonyms: | RAN HUMAN;RAN (E70A), HUMAN;RAS RELATED NUCLEAR PROTEIN, HUMAN;TC4, HUMAN;RAS-RELATED NUCLEAR PROTEIN (E70A), HUMAN;TC4 (E70A), HUMAN;Ras related nuclear protein;TC4 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![TC4, HUMAN Structure]() |
| | TC4, HUMAN Chemical Properties |
| storage temp. | −70°C | | form | buffered aqueous glycerol solution |
| Safety Statements | 24/25 | | WGK Germany | 1 |
| | TC4, HUMAN Usage And Synthesis |
| Description | RAN Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 236 amino acids (1-216 a.a.) and having a molecular mass of 26.5 kDa. The RAN is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | RAN is a GTP-binding protein that participates in nucleocytoplasmic transport. RAN is necessary for the import of protein into the nucleus and also for RNA export. RAN takes part in chromatin condensation and control of cell cycle. The RAN complex with BIRC5 participates in mitotic spindle formation by being as a physical scaffold to assist the delivery of the RAN effector molecule TPX2 to microtubules. RUN increases AR-mediated transactivation. |
| | TC4, HUMAN Preparation Products And Raw materials |
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