2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione

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2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione Basic information
Product Name:2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione
Synonyms:2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 4-nitro-2-(tetrahydro-2,6-dioxo-2H-pyran-3-yl)-
CAS:6383-80-8
MF:C13H8N2O7
MW:304.21
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Mol File:6383-80-8.mol
2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione Structure
2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione Chemical Properties
Boiling point 579.1±45.0 °C(Predicted)
density 1.703±0.06 g/cm3(Predicted)
solubility DMF; DMSO
form Solid
pka-3.98±0.20(Predicted)
color Yellow
Safety Information
MSDS Information
2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione Usage And Synthesis
Uses2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione is an intermediate in the synthesis of Pomalidomide (P688200), a thalidomide derivative and a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.
2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)-4-nitroisoindoline-1,3-dione Preparation Products And Raw materials
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