TrkA-IN-1 manufacturers
- TrkA-IN-1
-
- $1430.00
-
2026-05-11
- CAS:1680179-43-4
- Purity:
- Supply Ability: 10g
- TrkA-IN-1
-
- $1430.00
-
2025-07-31
- CAS:1680179-43-4
- Purity:
- Supply Ability: 10g
|
| | TrkA-IN-1 Basic information |
| Product Name: | TrkA-IN-1 | | Synonyms: | TrkA-IN-1;TrkA IN 1,TrkAIN1;Urea, N-9H-fluoren-9-yl-N'-(2-methyl-4-phenyl-5-pyrimidinyl)- | | CAS: | 1680179-43-4 | | MF: | C25H20N4O | | MW: | 392.45 | | EINECS: | | | Product Categories: | | | Mol File: | 1680179-43-4.mol |  |
| | TrkA-IN-1 Chemical Properties |
| Boiling point | 597.0±50.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 8.33 mg/mL (21.23 mM) | | pka | 11.90±0.70(Predicted) | | form | Solid | | color | White to yellow |
| | TrkA-IN-1 Usage And Synthesis |
| Uses | TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1]. | | IC 50 | TrkA: 99 nM (IC50); TrkB: 81 μM (IC50); TrkC: 25 μM (IC50) | | References | [1] Su HP , et al. Structural characterization of nonactive site, TrkA-selective kinase inhibitors. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):E297-E306. DOI:10.1073/pnas.1611577114 |
| | TrkA-IN-1 Preparation Products And Raw materials |
|