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Varanous Labs Pvt Ltd
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+91-7036248882 +91-7036248882 |
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bheemashankar.e@varanouslabs.com |
| Products Intro: |
Product Name:2,6-Di fluoro Dolutegravir
CAS:2244161-72-4
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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Dolutegravir Impurity 8 manufacturers
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| | Dolutegravir Impurity 8 Basic information |
| Product Name: | Dolutegravir Impurity 8 | | Synonyms: | 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity);2,6-Di fluoro Dolutegravir;2,6 Difluoro dolutegravir sodium salt;4-Desfluoro-6-fluoro DolutegravirQ: What is
4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of
4-Desfluoro-6-fluoro Dolutegravir;(4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;Dolutegravir 2,6-difluoro Impurity;Dolutegravir Impurity 59 | | CAS: | 2244161-72-4 | | MF: | C20H19F2N3O5 | | MW: | 419.38 | | EINECS: | | | Product Categories: | | | Mol File: | 2244161-72-4.mol |  |
| | Dolutegravir Impurity 8 Chemical Properties |
| Boiling point | 664.9±55.0 °C(Predicted) | | density | 1.53±0.1 g/cm3(Predicted) | | pka | 4.50±1.00(Predicted) |
| | Dolutegravir Impurity 8 Usage And Synthesis |
| Uses | 4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. |
| | Dolutegravir Impurity 8 Preparation Products And Raw materials |
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