A 410099.1, amine manufacturers
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| | A 410099.1, amine Basic information |
| Product Name: | A 410099.1, amine | | Synonyms: | A 410099.1, amine;A 410099.1, amine-Boc hydrochloride;tert-Butyl ((S)-1-(((S)-2-((2S,4S)-4-amino-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate hydrochloride | | CAS: | 2374122-37-7 | | MF: | C32H50ClN5O5 | | MW: | 620.23 | | EINECS: | | | Product Categories: | | | Mol File: | 2374122-37-7.mol |  |
| | A 410099.1, amine Chemical Properties |
| solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | A 410099.1, amine Usage And Synthesis |
| Uses | A 410099.1, amine-Boc hydrochloride is afunctionalizedIAP ligand and can be used for the synthesis of PROTACs, such as PROTACs targeting BTK (PROTACs 4 and 5)[1]. | | IC 50 | cIAP1 | | storage | Store at -20°C | | References | [1] Christopher P Tinworth, et al. PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding. ACS Chem Biol.2019 Mar 15;14(3):342-347 DOI:10.1021/acschembio.8b01094 |
| | A 410099.1, amine Preparation Products And Raw materials |
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