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| | 2,5-Dichlorophenol Basic information |
| | 2,5-Dichlorophenol Chemical Properties |
| Melting point | 54-57 °C (lit.) | | Boiling point | 211 °C (lit.) | | density | 1.3446 (rough estimate) | | refractive index | 1.4430 (estimate) | | Fp | 100 °C | | storage temp. | 0-6°C | | solubility | 2000mg/l (experimental) | | pka | 7.53±0.10(Predicted) | | form | Crystals | | color | White to light brown | | Water Solubility | 3 g/L (20 ºC) | | BRN | 1907692 | | Henry's Law Constant | 1.6×100 mol/(m3Pa) at 25℃, HSDB (2015) | | InChI | 1S/C6H4Cl2O/c7-4-1-2-5(8)6(9)3-4/h1-3,9H | | InChIKey | RANCECPPZPIPNO-UHFFFAOYSA-N | | SMILES | Oc1cc(Cl)ccc1Cl | | LogP | 3.06 at 20℃ | | CAS DataBase Reference | 583-78-8(CAS DataBase Reference) | | NIST Chemistry Reference | Phenol, 2,5-dichloro-(583-78-8) | | EPA Substance Registry System | 2,5-Dichlorophenol (583-78-8) |
| Hazard Codes | C,N,Xn | | Risk Statements | 22-34-51/53-36/38 | | Safety Statements | 26-36/37/39-45-61-37/39 | | RIDADR | UN 2020 6.1/PG 3 | | WGK Germany | 2 | | RTECS | SK8600000 | | TSCA | TSCA listed | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29081000 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2 | | Hazardous Substances Data | 583-78-8(Hazardous Substances Data) | | Toxicity | LD50 orally in Rabbit: 580 mg/kg |
| | 2,5-Dichlorophenol Usage And Synthesis |
| Chemical Properties | white to light brown crystals | | Uses | 2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides. | | Uses | 2,5-Dichlorophenol may be used as an analytical reference standard for the determination of the analyte in water, and wood, paper, cardboard, fruits, and fruit juices using simultaneous dispersive liquid-liquid microextraction and derivatization followed by gas chromatography-electron-capture detection (GC-ECD) and gas chromatography-mass spectrometry (GC-MS), respectively. | | Definition | ChEBI: A dichlorophenol with the chloro substituents at positions 2 and 5. | | Synthesis Reference(s) | Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052 | | General Description | Prisms (from benzene, petroleum ether) or white crystals. Odor threshold 30 μg/L at 68-72°F; 33 μg/L at 86°F. Taste threshold 0.5 μg/L. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | 2,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents. | | Fire Hazard | Flash point data for 2,5-Dichlorophenol are not available. 2,5-Dichlorophenol is probably combustible. | | Purification Methods | Crystallise it from ligroin and sublime it in a vacuum or distil it. [Beilstein 6 IV 942.] |
| | 2,5-Dichlorophenol Preparation Products And Raw materials |
| Raw materials | Sodium nitrate-->2,4-Dichlorophenol-->2,5-Dichloroaniline-->NITROUS ACID-->Sodium 2,4,5-trichlorobenzenesulphonate-->Diphosphate-->3,4-DICHLOROANISOLE-->2,5-DICHLOROANISOLE-->2,4-DICHLOROANISOLE-->2-Bromo-1,4-dichlorobenzene-->3,4-Dichlorophenol-->3-Chlorophenol-->3,7-Dichlorodibenzofuran | | Preparation Products | Dicamba-->3,6-DICHLORO-2-HYDROXY BENZOIC ACID-->4-Bromo-2,5-dichlorophenol-->3,5-Dichlorophenol-->2,4,5-Trichlorophenoxyacetic acid-->2,3,4,6-TETRACHLOROPHENOL-->3,6-DICHLOROCATECHOL |
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