- Ile-NCA
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2026-09-11
- CAS:51248-35-2
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1T+
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| | 4-isobutyloxazolidine-2,5-dione Basic information |
| Product Name: | 4-isobutyloxazolidine-2,5-dione | | Synonyms: | 4-isobutyloxazolidine-2,5-dione;Einecs 257-083-3;NCA of N-carboxyanhydride of raceMic DL-leucine;4-(2-Methylpropyl)-2,5-oxazolidinedione;ILE-NCA;H-DL-Leu-NCA;4-(2-methylpropyl)oxazolidine-2,5-dione;Isobutyloxazolidine-2,5-dione | | CAS: | 51248-35-2 | | MF: | C7H11NO3 | | MW: | 157.17 | | EINECS: | 257-083-3 | | Product Categories: | | | Mol File: | 51248-35-2.mol |  |
| | 4-isobutyloxazolidine-2,5-dione Chemical Properties |
| Melting point | 47-48 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4)) | | density | 1.124±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 9.38±0.40(Predicted) |
| | 4-isobutyloxazolidine-2,5-dione Usage And Synthesis |
| Preparation | A solution of phosgene(12.5% in toluene, 25 mL, 31.6 mmol) was added to a suspension of l-leucine (1.31 g, 10 mmol) in dioxane (30 mL) and ethyl acetate (25 mL) at 40 ℃ under a static atmosphere of nitrogen. After 4 h, the leucine had dissolved and then the excess phosgene was removed in a stream of nitrogen. The solvent was removed at 40 ℃ in vacuo and the residue was recrystallized from diethyl ether/light petroleum (bp 40–60 ℃) to yield colorless needles of 4-(2-methylpropyl)oxazolidine-2,5-dione (1.01 g, 69%). |
| | 4-isobutyloxazolidine-2,5-dione Preparation Products And Raw materials |
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