1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate

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1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate Basic information
Product Name:1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate
Synonyms:1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate;Nonadecanedioic acid, 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]-, 1,19-bis(1-hexylheptyl) ester;Lipid 2-10;1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate(LP-01);Di(tridecan-7-yl) 10-(N-(3-(dimethylamino)propyl)octanamido)nonadecanedioate
CAS:2055939-68-7
MF:C58H114N2O5
MW:919.54
EINECS:
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Mol File:2055939-68-7.mol
1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate Structure
1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate Chemical Properties
Boiling point 849.7±40.0 °C(Predicted)
density 0.914±0.06 g/cm3(Predicted)
solubility Chloroform: Sparingly soluble: 1-10 mg/ml
Methanol: Sparingly soluble: 1-10 mg/ml
form Liquid
pka9.44±0.28(Predicted)
color Colorless to light yellow
Safety Information
MSDS Information
1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate Usage And Synthesis
UsesIonizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure[1].
References[1] Thomas D Madden, et al. Lamellar lipid nanoparticles. Patent WO2019089828A1.
[2] BANERJEE S, PILLAI J. Lipid Nanoparticle Formulations for Enhanced Antituberculosis Therapy[C]. 1900: 0. DOI: 10.1016/b978-0-323-47347-7.00011-2
1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate Preparation Products And Raw materials
Tag:1,19-Bis(1-hexylheptyl) 10-[[3-(dimethylamino)propyl](1-oxooctyl)amino]nonadecanedioate(2055939-68-7) Related Product Information
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