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| | 1H-Isoindole-4-carboxaldehyde, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo- Basic information |
| Product Name: | 1H-Isoindole-4-carboxaldehyde, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo- | | Synonyms: | 1H-Isoindole-4-carboxaldehyde, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-;2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindole-4-carbaldehyde;Thalidomide-4-carbaldehyde;2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindole-4-carboxaldehyde;2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindoline-4-carbaldehyde | | CAS: | 2369068-46-0 | | MF: | C14H10N2O5 | | MW: | 286.24 | | EINECS: | | | Product Categories: | | | Mol File: | 2369068-46-0.mol |  |
| | 1H-Isoindole-4-carboxaldehyde, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo- Chemical Properties |
| Boiling point | 588.3±45.0 °C(Predicted) | | density | 1.560±0.06 g/cm3(Predicted) | | pka | 10+-.0.40(Predicted) |
| | 1H-Isoindole-4-carboxaldehyde, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo- Usage And Synthesis |
| Uses | Thalidomide-4-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions. |
| | 1H-Isoindole-4-carboxaldehyde, 2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo- Preparation Products And Raw materials |
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