Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt

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Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt Basic information
Product Name:Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt
Synonyms:Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt;CAP GAG（3'OMe） m7(3'OMeG)(5')ppp(5')(2'OMeA)pG 100mM Ammonium Solution, GMP grade;CAP GAG（3'OMe） m7(3'OMeG)(5')ppp(5')(2'OMeA)pG 100mM Ammonium Solution;CAP GAG(3'OMe) m7(3'OMeG)(5')ppp(5')(2'OMeA)pG 100mM Tris Solution
CAS:2089461-55-0
MF:C33H45N15O24P4
MW:1159.7
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Mol File:2089461-55-0.mol
Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt Structure
Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt Chemical Properties
InChIKeyQLKZOMAEOBMBOC-PNOGKYMXNA-N
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Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt Usage And Synthesis
Uses3'OMe-m7GpppAmpG is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG shows a significant translational efficiency. 3'OMe-m7GpppAmpG can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization[1].
References[1] Senthilvelan A, et al. Trinucleotide Cap Analogue Bearing a Locked Nucleic Acid Moiety: Synthesis, mRNA Modification, and Translation for Therapeutic Applications. Org Lett. 2021 Jun 4;23(11):4133-4136. DOI:10.1021/acs.orglett.1c01037
Guanosine, 7-methylguanylyloxyphosphinicooxyphosphinico-(5'→5')-2'-O-methyladenylyl-(3'→5')-, inner salt Preparation Products And Raw materials
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