2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol

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2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol Basic information
Product Name:2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol
Synonyms:FLUOROUS CHEMICAL PHOSPHORYLATION REAGENT II;F-CPR-II CEP;Propanedioic acid, 2-[[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]methyl]-2-[[[4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl]bis(4-methoxyphenyl)methoxy]methyl]-, 1,3-diethyl ester;((((E)-2-((2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(((2-cyanoethoxy)(diisopropylamino)phosphanyl)oxy)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate);2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol
CAS:1027512-47-5
MF:C49H54F17N2O9P
MW:1168.91
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Mol File:Mol File
2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol Structure
2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol Chemical Properties
Boiling point 813.7±65.0 °C(Predicted)
pka2.85±0.70(Predicted)
Safety Information
MSDS Information
2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol Usage And Synthesis
UsesF-CPR-II CEP allows a combination of fluorous affinity purification with concomitant 5''-phosphorylation, which is especially attractive when synthesizing longmers that will be used in ligase reactions. It may also be utilized as a common handle for fluorous purification, obviating the need to choose a different fluorous phosphoramidite for each different 5''-terminal nucleotide when a 5''-phosphate is tolerated in a particular application.
2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol Preparation Products And Raw materials
Tag:2,2'-Bis(ethoxycarbonyl)-1-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-3-O-[4,4'-dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl]-1,3-propanediol(1027512-47-5) Related Product Information