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| | ZXH-4-137 Basic information |
| Product Name: | ZXH-4-137 | | Synonyms: | ZXH-4-137;(2S,4R)-1-[(2S)-2-(11-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}undecanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide | | CAS: | 2711006-74-3 | | MF: | C47H60N6O9S | | MW: | 885.08 | | EINECS: | | | Product Categories: | | | Mol File: | 2711006-74-3.mol |  |
| | ZXH-4-137 Chemical Properties |
| Boiling point | 1082.7±65.0 °C(Predicted) | | density | 1.273±0.06 g/cm3(Predicted) | | pka | 10.70±0.40(Predicted) |
| | ZXH-4-137 Usage And Synthesis |
| Description | ZXH-4-137 is a PROTAC compound. | | Uses | ZXH-4-137 is a potent and selective CRBN degrader (PROTAC). | | References | [1] Powell CE, et al. Selective degradation-inducing probes for studying cereblon (CRBN) biology. RSC Med Chem. 2021 Jul 6;12(8):1381-1390. DOI:10.1039/d0md00382d |
| | ZXH-4-137 Preparation Products And Raw materials |
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