Lobelane Hydrochloride

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Lobelane Hydrochloride Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Lobelane Hydrochloride manufacturers
Lobelane Hydrochloride Basic information
Product Name:Lobelane Hydrochloride
Synonyms:Lobelane Hydrochloride
CAS:246244-19-9
MF:C22H29N.ClH
MW:343.93
EINECS:
Product Categories:
Mol File:246244-19-9.mol
Lobelane Hydrochloride Structure
Lobelane Hydrochloride Chemical Properties
Melting point 171-172 °C
Safety Information
MSDS Information
Lobelane Hydrochloride Usage And Synthesis
DescriptionLobelane Hydrochloride is an inhibitor of the vesicular monoamine transporter-2 (VMAT2).
UsesLobelane hydrochloride is a biologically active compound that has the activity of inhibiting vesicular monoamine transporter-2 (VMAT2). Lobelane hydrochloride has a low affinity for nicotinic acetylcholine receptors (nAChR), thereby enhancing its selectivity for VMAT2. Synthetic structural changes of lobelane hydrochloride have led to some related analogs that show mild changes in affinity for VMAT2. The most potent synthetic lobelane hydrochloride obtained after structural modification has a K(i) value of 630 nM, showing significant VMAT2 selectivity. The biological activity of lobelane hydrochloride suggests that it has the potential to be used in the development of compounds to inhibit methamphetamine abuse[1].
References[1] Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter
Lobelane Hydrochloride Preparation Products And Raw materials
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