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| | Ethanone, 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)-, hydrochloride (1:1) Basic information |
| Product Name: | Ethanone, 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)-, hydrochloride (1:1) | | Synonyms: | Ethanone, 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)-, hydrochloride (1:1);2-amino-1-(4-bromo-2,5-dimethoxyphenyl)-ethanone,monohydrochloride;bk-2C-B HCl (2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone Hydrochloride) 1.0 mg/ml in Methanol (as free base);bk-2C-B HCl (2-Amino-1-(4-bromo-2,5-dimethoxyphenyl)ethanone Hydrochloride);Bk-2C-B.HCl;Bk-2C-B.HCl, 1mg/ml in Methanol (as free base) | | CAS: | 2303508-66-7 | | MF: | C10H13BrClNO3 | | MW: | 310.57 | | EINECS: | | | Product Categories: | | | Mol File: | 2303508-66-7.mol |  |
| | Ethanone, 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)-, hydrochloride (1:1) Chemical Properties |
| solubility | DMSO: 2.5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml | | form | A crystalline solid |
| | Ethanone, 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)-, hydrochloride (1:1) Usage And Synthesis |
| Description | A series of 2,5-dimethoxyphenethylamines, substituted at the four position of the aromatic ring, have psychoactive effects.1,2 2C-B (hydrochloride) is a hallucinogenic designer drug that activates the serotonin receptor 5-HT2C (pEC50 = 6.8 for arachidonic acid release) and has emerged as a drug of abuse.1,2,3 bk-2C-B is a β-ketone analog of 2C-B.4 This product is intended for forensic and research purposes. | | References | 1. Bruno, R., Matthews, A.J., Dunn, M., et al. Emerging psychoactive substance use among regular ecstasy users in Australia Drug Alcohol Depend. 124(1-2),19-25(2012). 2. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors J. Pharmacol. Exp. Ther. 321(3),1054-1061(2007). 3. Maurer, H.H. Chemistry, pharmacology, and metabolism of emerging drugs of abuse Ther. Drug Monit. 32(5),544-549(2010). 4. Westphal, F., Junge, T., Girreser, U., et al. Structure elucidation of a new designer benzylpiperazine: 4-Bromo-2,5-dimethoxybenzylpiperazine Forensic Sci. Int. 187(1-3),87-96(2009). |
| | Ethanone, 2-amino-1-(4-bromo-2,5-dimethoxyphenyl)-, hydrochloride (1:1) Preparation Products And Raw materials |
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