| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Watanidipine dihydrochloride
CAS:133743-71-2
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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| Company Name: |
Leancare Ltd.
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| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
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| Company Name: |
2A PharmaChem USA
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| Tel: |
(630) 737-0988 |
| Email: |
sales@2apharmachem.com |
| Products Intro: |
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Vatanidipine hydrochloride manufacturers
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| | Vatanidipine hydrochloride Basic information |
| | Vatanidipine hydrochloride Chemical Properties |
| | Vatanidipine hydrochloride Usage And Synthesis |
| Uses | Vatanidipine (Watanidipine) hydrochloride is an orally active dihydropyridine (DHP)-type calcium channel blocker and a useful antihypertensive agent. Vatanidipine hydrochloride shows vasodilatory effects and also suppresses noradrenaline release from sympathetic nerve endings[1][2]. | | Definition | ChEBI: Vatanidipine hydrochloride is a diarylmethane. | | Safety Profile | A poison by ingestion,
intraperitoneal, and subcutaneous routes.
When heated to decomposition it emits
toxic vapors of NOx. | | in vivo | Vatanidipine (1-10 mg/kg, p.o.) suppresses the systolic blood pressure of spontaneously hypertensive rats[1].
| | References | [1] Matsumura Y, et al. Vatanidipine hydrochloride: a new long-lasting antihypertensive agent. Expert Opin Investig Drugs. 2001 Jan;10(1):139-55. DOI:10.1517/13543784.10.1.139
[2] H Shinyama, et al. Effects of the calcium antagonist AE0047 on the development of neurological deficit and infarction after middle cerebral artery occlusion in stroke-prone spontaneously hypertensive rats. J Pharm Pharmacol. 1997 Sep;49(9):919-24. DOI:10.1111/j.2042-7158.1997.tb06136.x |
| | Vatanidipine hydrochloride Preparation Products And Raw materials |
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