- Bruceantin
-
- $107.00 / 1mg
-
2026-04-20
- CAS:41451-75-6
- Min. Order:
- Purity: 98.94%
- Supply Ability: 10g
- Bruceantin
-
- $320.00 / 10mg
-
2022-02-14
- CAS:41451-75-6
- Min. Order: 10mg
- Purity: 98% by HPLC
- Supply Ability: 1000.00 kgs
- Bruceantin
-
- $0.00 / 1Kg
-
2020-05-03
- CAS:41451-75-6
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 800 ton
|
| | Bruceantin Basic information |
| Product Name: | Bruceantin | | Synonyms: | 2H-3,11c-(Epoxymethano)phenanthro[10,1-bc]pyran, picras-3-en-21-oic acid deriv.;NCI 165563;NSC 165563;Yadanziyou Oleum Bruceae;Bruceantin;Crow gall Pavilion;Bruceantin(NSC165563);Picras-3-en-21-oic acid, 15-[[(2E)-3,4-dimethyl-1-oxo-2-penten-1-yl]oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxo-, methyl ester, (11β,12α,15β)- | | CAS: | 41451-75-6 | | MF: | C28H36O11 | | MW: | 548.58 | | EINECS: | | | Product Categories: | | | Mol File: | 41451-75-6.mol |  |
| | Bruceantin Chemical Properties |
| Melting point | 225-226℃ | | alpha | D25 -43° (c = 0.31 in pyridine) | | Boiling point | 540.78°C (rough estimate) | | density | 1.2262 (rough estimate) | | refractive index | 1.5970 (estimate) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 8.81±0.70(Predicted) | | form | Solid | | color | White to Off-White |
| Toxicity | LD50 in male, female mice (mg/kg): 1.95, 2.58 i.v. (Castles) |
| | Bruceantin Usage And Synthesis |
| Uses | Bruceantin is a pharmacological agent which has been shown to induce apoptosis in human promyelocytic leukemia cells. Antiamoebic agent. | | Definition | ChEBI: Bruceantin is a triterpenoid. | | in vivo | Bruceantin (1.25-12 mg/kg, ip, every 3 days for 40 days) exhibits antitumor effect in mouse RPMI 8226 xenograft models[1]. | Animal Model: | Mouse RPMI 8226 xenograft models[1] | | Dosage: | 1.25-12 mg/kg | | Administration: | ip, every 3 days for 40 days | | Result: | Inhibited tumor growth. |
|
| | Bruceantin Preparation Products And Raw materials |
|