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2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid

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Products Intro: Product Name:Fmoc-L-Thr-OH
CAS:73731-37-0
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Products Intro: Product Name:N-(9-Fluorenylmethoxycarbonyl)-L-threonine
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CAS:73731-37-0
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  • Fmoc-L-threonine
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  • 2026-05-15
  • CAS:73731-37-0
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  • Fmoc-L-Thr-OH
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  • 2026-05-14
  • CAS:73731-37-0
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2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Basic information
Product Name:2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid
Synonyms:FMOC-L-THREONINE extrapure;N-(9-Fluorenylmethoxycarbonyl)-L-threonine ,99%;N-alpha-(9-fluorenylmethyloxycarbonylamino)-3-hydroxybutanoic acid;Fmoc-L-threonine ,99%;Fmoc-L-Threonine monohydrate ,99%;Fmoc-Threonine-OH;2-(9H-Fluoren-9-ylMethoxycarbony-laMino)-3-;FMoc-Thr-OH·H2O FMoc-L-threonine Monohydrate
CAS:73731-37-0
MF:C19H19NO5
MW:341.36
EINECS:1533716-785-6
Product Categories:Amino Acid Derivatives;Amino Acids;Threonine [Thr, T];Fmoc-Amino Acids and Derivatives;Amino Acids (N-Protected);Biochemistry;Fmoc-Amino Acids;Fmoc-Amino acid series
Mol File:73731-37-0.mol
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Structure
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Chemical Properties
Melting point 115°C (dec.)
alpha -16 º (c=1%, DMF)
Boiling point 596.5±50.0 °C(Predicted)
density 1.327±0.06 g/cm3(Predicted)
refractive index -15.5 ° (C=1, DMF)
storage temp. 2-8°C
solubility soluble in Methanol
pka3.49±0.10(Predicted)
form powder to crystal
color White to Almost white
Optical Rotation[α]20/D 16±1°, c = 1% in DMF
BRN 4300093
Major Applicationpeptide synthesis
InChI1S/C19H19NO5.H2O/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16;/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23);1H2/t11-,17+;/m1./s1
InChIKeyCGNQPFAECJFQNV-NRNQBQMASA-N
SMILESO.C[C@@H](O)[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
CAS DataBase Reference73731-37-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-26
WGK Germany 3
HS Code 29242990
Storage Class13 - Non Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid Usage And Synthesis
Chemical PropertiesWhite powder
UsesN-Fmoc-L-threonine is an N-Fmoc-protected form of L-Threonine (T405500). L-Threonine is an essential amino acid that is commonly used as a feed and food additive. L-Threonine is produced in mass quantities by mutant Escherichia coli strains for research and food nutrition purposes. L-Threonine can be naturally found in fish and poultry, and is incorporated in some important proteins in the human body (such as hemoglobin and insulin).
reaction suitabilityreaction type: Fmoc solid-phase peptide synthesis
References[1] European Journal of Organic Chemistry, 2011, # 20-21, p. 3685 - 3689
[2] Tetrahedron, 2012, vol. 68, # 2, p. 697 - 704
[3] ChemBioChem, 2018, vol. 19, # 11, p. 1142 - 1146
[4] Tetrahedron Letters, 1993, vol. 34, # 24, p. 3837 - 3840
[5] Australian Journal of Chemistry, 2011, vol. 64, # 6, p. 723 - 731
Tag:2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-hydroxy-butanoic acid(73731-37-0) Related Product Information
FMOC-AMINOXYACETIC ACID Fmoc-L-Serine Fmoc-Gly-OH Fmoc-Leu-OH FMOC-S-trityl-L-cysteine Fmoc-Asp(OtBu)-OH FMOC-L-Methionine Fmoc-Trp(Boc)-OH Nalpha-Fmoc-Ndelta-trityl-L-glutamine Fmoc-Tyr(tBu)-OH Nalpha-FMOC-L-Tryptophan Fmoc-Phe-OH Fmoc-Pro-OH Fmoc-L-glutamic acid 5-tert-butyl ester FMOC-O-tert-Butyl-L-threonine Fmoc-N-methyl-O-benzyl-L-threonine O-(2-Azido-4,6-O-benzylidene-2-deoxy-alpha-D-galactopyranosyl)-N-Fmoc-L-threonine tert-Butyl Ester L-Threonine