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| | Ezetimibe hydroxy-b-D-glucuronide Basic information |
| Product Name: | Ezetimibe hydroxy-b-D-glucuronide | | Synonyms: | EZETIMIBE HYDROXY GLUCURONIDE;(2S,3S,4S,5R,6R)-6-((S)-1-(4-Fluorophenyl)-3-((2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4;(2S,3S,4S,5R,6S)-6-((S)-1-(4-fluorophenyl)-3-((2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxoazetidin-3-yl)propoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid;(1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl b-D-Glucopyranosiduronic Acid;Ezetimibe Hydroxy b-D-Glucuronide;SCH 488128;(1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl -D-Glucopyranosiduronic Acid;Ezetimibe Hydroxy -D-Glucuronide | | CAS: | 536709-33-8 | | MF: | C30H29F2NO9 | | MW: | 585.55 | | EINECS: | | | Product Categories: | Glucuronides;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 536709-33-8.mol |  |
| | Ezetimibe hydroxy-b-D-glucuronide Chemical Properties |
| Melting point | 127-129°C | | Boiling point | 863.740±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.547±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 2.806±0.70(predicted) | | color | Off-White |
| | Ezetimibe hydroxy-b-D-glucuronide Usage And Synthesis |
| Description | Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe . | | Chemical Properties | Off-White Solid | | Uses | A metabolite of Ezetimibe. Antilipemic. | | References | [1] TAKAKO FURUKAWA. Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data[J]. Drug Metabolism and Pharmacokinetics, 2012, 27 2: Pages 171-180. DOI: 10.2133/dmpk.dmpk-11-rg-088 |
| | Ezetimibe hydroxy-b-D-glucuronide Preparation Products And Raw materials |
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