| Company Name: |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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| Tel: |
17702719238 |
| Email: |
sales@sun-shinechem.com |
| Products Intro: |
Product Name:Zemprocitinib
CAS:2417414-44-7
Purity:98.0% Package:50.0mg 100.0mg 200.0mg 500.0mg 1.0g
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Zemprocitinib
CAS:2417414-44-7
Package:50mg/RMB 16800
|
| Company Name: |
ChemOrigin Pharm
|
| Tel: |
15026428026 19002516454 |
| Email: |
ChemOrigin@126.com |
| Products Intro: |
Product Name:Zemprocitinib (LNK01001)
CAS:2417414-44-7
Purity:99% Package:100mg Remarks:1g; 2g; 5g
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| | 1-Propanesulfonamide, N-[3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)bicyclo[1.1.1]pent-1-yl]- Basic information |
| | 1-Propanesulfonamide, N-[3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)bicyclo[1.1.1]pent-1-yl]- Chemical Properties |
| Boiling point | 546.4±60.0 °C(Predicted) | | density | 1.66±0.1 g/cm3(Predicted) | | pka | 10.90±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | 1-Propanesulfonamide, N-[3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)bicyclo[1.1.1]pent-1-yl]- Usage And Synthesis |
| Uses | Zemprocitinib (Compound 1) is a Janus kinase (JAK) inhibitor. The IC50 values for JAK1, JAK2 and TYK2 are 5.95, 141.3 and 119 nM, respectively[1]. | | IC 50 | JAK1: 5.95 nM (IC50); JAK2: 141.3 nM (IC50); Tyk2: 119 nM (IC50) | | References | [1] Zhaokui WAN, et al. Tricyclic janus kinase 1 inhibitors, and compositions and methods thereof. WO2020088659A1. 2020-05-07. |
| | 1-Propanesulfonamide, N-[3-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)bicyclo[1.1.1]pent-1-yl]- Preparation Products And Raw materials |
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