4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester

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4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester manufacturers

  • TA-1801
  • TA-1801 pictures
  • $2500.00
  • 2026-04-21
  • CAS:88352-44-7
  • Purity:
  • Supply Ability: 10g
  • TA-1801
  • TA-1801 pictures
  • $2500.00
  • 2025-07-27
  • CAS:88352-44-7
  • Purity:
  • Supply Ability: 10g
4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester Basic information
Product Name:4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester
Synonyms:4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester;ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxzoleacetate;TA-1801;TA1801,TA 1801;Ethyl 2-(4-chlorophenyl)-5-(2-furyl)oxazole-4-acetate
CAS:88352-44-7
MF:C17H14ClNO4
MW:331.75
EINECS:
Product Categories:
Mol File:88352-44-7.mol
4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester Structure
4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester Chemical Properties
Melting point 107-108 °C(Solv: ethanol (64-17-5))
Boiling point 471.0±55.0 °C(Predicted)
density 1.275±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka-1.21±0.26(Predicted)
Safety Information
MSDS Information
4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester Usage And Synthesis
UsesTA-1801 is a hypolipidemic agent.
in vivo

TA-1801 reduces serum cholesterol and triglyceride levels by 23% and 35%, respectively, at a dose of 0.05% in a diet in normal rats, and it is about 10 times more active in hereditary hyperlipidemic rats (THLR/1) than in normal rats[1].

References[1] Moriya T, et al. Synthesis of ethyl 2-(4-chlorophenyl)-5-(2-furyl)-4-oxazoleacetate, a hypolipidemic agent, and related compounds. J Med Chem. 1988 Jun;31(6):1197-204. DOI:10.1021/jm00401a021
4-Oxazoleacetic acid, 2-(4-chlorophenyl)-5-(2-furanyl)-, ethyl ester Preparation Products And Raw materials
Raw materialsethyl 3-(4-chlorobenzoylamino)-4-(2-furyl)-4-oxobutyrate-->2-amino-1-(furan-2-yl)ethanone hydrochloride
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