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| | NSC10978 Basic information |
| Product Name: | NSC10978 | | Synonyms: | NSC10978;1,2-dibroMo-4-nitrobenzen;2-DIBROMO-4-NITROBENZENE;Benzene, 1,2-dibromo-4-nitro-;3,4-Dibromo-1-nitrobenzene | | CAS: | 5411-50-7 | | MF: | C6H3Br2NO2 | | MW: | 280.9 | | EINECS: | | | Product Categories: | | | Mol File: | 5411-50-7.mol |  |
| | NSC10978 Chemical Properties |
| Melting point | 58.5°C | | Boiling point | 296°C (rough estimate) | | density | 2.2414 (rough estimate) | | refractive index | 1.6400 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | form | solid | | color | White |
| | NSC10978 Usage And Synthesis |
| Chemical Properties | Yellow needle-like or flaky crystals. Melting point 58-59°C, boiling point 296°C, 180°C (2.66kPa), relative density 2.354 (8/4°C), refractive index 1.9853 (111°C). Soluble in ethanol, benzene and acetic acid, insoluble in water. Can sublimate and volatilize with water vapor. | | Synthesis | The general procedure for the synthesis of 1,2-dibromo-4-nitrobenzene from 4-nitrophthalic acid was as follows: 4-nitrophthalic acid (1 mmol), bromoisocyanuric acid ester, additives, and solvent (10 ml) were added to a round-bottom flask equipped with a Dimroth condenser (cooled to 10°C). The reaction mixture was heated under magnetic stirring in an oil bath at 120 °C for 60 h under fluorescent room light irradiation (FL). Upon completion of the reaction, the cooled mixture was filtered through a short silica gel pad, washed with 1 M aqueous Na2SO3 solution, dried over Na2SO4, filtered and concentrated in vacuum to give the crude product 1,2-dibromo-4-nitrobenzene. The crude product can be further purified by silica gel chromatography. The experimental results are detailed in Table 6. | | References | [1] Patent: WO2017/60905, 2017, A1. Location in patent: Paragraph 00164 |
| | NSC10978 Preparation Products And Raw materials |
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