4-(3-phenanthryl)butanoic acid

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4-(3-phenanthryl)butanoic acid Basic information
Product Name:4-(3-phenanthryl)butanoic acid
Synonyms:4-(3-phenanthryl)butanoic acid;HIV-1 Nef-IN-1;NSC-92828;4-(Phenanthren-3-yl)butanoic acid;3-Phenanthrenebutyric acid;antiviral,HIV 1 Nef IN 1,SH3,HIV1 NefIN1,HIV,PPI,Nef,Inhibitor,inhibit,HIV-1,Human immunodeficiency virus;HIV-1 Nef-IN-1, 10 mM in DMSO
CAS:13728-56-8
MF:C18H16O2
MW:264.32
EINECS:
Product Categories:
Mol File:13728-56-8.mol
4-(3-phenanthryl)butanoic acid Structure
4-(3-phenanthryl)butanoic acid Chemical Properties
Melting point 138-139 °C
Boiling point 487.2±14.0 °C(Predicted)
density 1.211±0.06 g/cm3(Predicted)
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
pka4.76±0.10(Predicted)
color Pale Yellow ti Light Yellow
InChIInChI=1S/C18H16O2/c19-18(20)7-3-4-13-8-9-15-11-10-14-5-1-2-6-16(14)17(15)12-13/h1-2,5-6,8-12H,3-4,7H2,(H,19,20)
InChIKeyNYIVWTWKIQOBKO-UHFFFAOYSA-N
SMILESC1=C2C(C3C(C=C2)=CC=CC=3)=CC(CCCC(O)=O)=C1
Safety Information
MSDS Information
4-(3-phenanthryl)butanoic acid Usage And Synthesis
Uses3-Phenanthrenebutanoic Acid is an intermediate in the synthesis of novel polycyclic aromatic isomers of benz[a]anthracene containing a cyclopenta-fused ring.
IC 50HIV-1 Nef: 6.7 μM (Kd)
4-(3-phenanthryl)butanoic acid Preparation Products And Raw materials
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Ritonavir Gag-Pol polyprotein, HIV (440a.a, His) P24 protein, HIV-1 (BAH97658, HIS) Rev Protein, HIV-1 group M subtype C (GST) ENVELOPE GLYCOPROTEIN GP120 Protein, HIV-1 (AAC57427, HEK293, HIS) P24 protein, HIV-1 (AAB50258, HIS)