| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:(1'S,2'S)-Nicotine 1'-Oxide CAS:51095-86-4 Package:100Mg,1g
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| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:(1'S,2'S)-NICOTINE 1'-OXIDE CAS:51095-86-4 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | (1'S,2'S)-NICOTINE 1'-OXIDE Basic information |
| | (1'S,2'S)-NICOTINE 1'-OXIDE Chemical Properties |
| Melting point | 182-183°C | | storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere | | solubility | DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml | | pka | 4.63±0.40(Predicted) | | form | A crystalline solid | | color | White to off-white | | Stability: | Hygroscopic |
| | (1'S,2'S)-NICOTINE 1'-OXIDE Usage And Synthesis |
| Chemical Properties | Off-White to Yellow Solid | | Uses | Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine | | Uses | Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans. | | Definition | ChEBI: Trans-(S)-nicotine N(1')-oxide is an (S)-nicotine N(1')-oxide in which the N(1')-methyl group is on the opposite side of the pyrrolidine ring to the pyridine substituent. The major species at pH 7.3. |
| | (1'S,2'S)-NICOTINE 1'-OXIDE Preparation Products And Raw materials |
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