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| | bequinostatin A Basic information |
| Product Name: | bequinostatin A | | Synonyms: | bequinostatin A;Benzo[a]naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-1,6,7,9,11-pentahydroxy-8,13-dioxo-3-pentyl-, (-)- (9CI) | | CAS: | 151013-37-5 | | MF: | C28H24O9 | | MW: | 504.48 | | EINECS: | | | Product Categories: | | | Mol File: | 151013-37-5.mol |  |
| | bequinostatin A Chemical Properties |
| solubility | DMSO: Soluble; Methanol: Soluble; Pyridine: Soluble | | form | A solid |
| | bequinostatin A Usage And Synthesis |
| Description | Bequinostatin A is a naphthoquinone originally isolated from Streptomyces and a glutathione S-transferase pi 1 (GSTP1) inhibitor (IC50 = 0.6 μg/ml for human GSTP1).1 | | Uses | Bequinostatin A is a benzo[a]naphthacenequinone metabolite that can be isolated from Streptomyces sp. MI384-DF12. Bequinostatin A shows considerable inhibitory activity against human pi class glutathione S-transferase (GST pi)[1]. | | References | 1. Aoyama, T., Kojima, F., Abe, F., et al. Bequinostatins A and B new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities J. Antibiot. (Tokyo) 46(6),914-920(1993). |
| | bequinostatin A Preparation Products And Raw materials |
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