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| | halenaquinone Basic information |
| Product Name: | halenaquinone | | Synonyms: | halenaquinone;(S)-12bβ-Methyl-1H-5-oxabenzo[k]acephenanthrylene-3,6,8,11(2H,12bH)-tetrone;1H-Benzo[6,7]phenanthro[10,1-bc]furan-3,6,8,11(2H,12bH)-tetrone, 12b-methyl-, (12bS)- | | CAS: | 86690-14-4 | | MF: | C20H12O5 | | MW: | 332.31 | | EINECS: | | | Product Categories: | | | Mol File: | 86690-14-4.mol |  |
| | halenaquinone Chemical Properties |
| Boiling point | 601.2±55.0 °C(Predicted) | | density | 1.501±0.06 g/cm3(Predicted) |
| | halenaquinone Usage And Synthesis |
| Uses | Halenaquinone is a phosphatidylinositol 3-kinase inhibitor and can be isolated from the marine sponge Petrosia alfiani. Halenaquinone inhibits RANKL-induced osteoclastogenesis, and induces cell apoptosis in PC12 cells[1][2][3]. | | References | [1] Deborah M. Roll, et al. Halenaquinone, a pentacyclic polyketide from a marine sponge. ：Journal of the American Chemical Society.Vol 105/Issue 19.
[2] Tsukamoto S, et al. Halenaquinone inhibits RANKL-induced osteoclastogenesis. Bioorg Med Chem Lett. 2014;24(22):5315-5317. DOI:10.1016/j.bmcl.2014.09.043
[3] Fujiwara H, et al. Halenaquinone, a novel phosphatidylinositol 3-kinase inhibitor from a marine sponge, induces apoptosis in PC12 cells. Eur J Pharmacol. 2001;413(1):37-45. DOI:10.1016/s0014-2999(00)00944-4 |
| | halenaquinone Preparation Products And Raw materials |
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