N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide

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N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide Basic information
Product Name:N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide
Synonyms:PXT-012253
CAS:1835647-08-9
MF:C13H11ClN2OS
MW:278.76
EINECS:
Product Categories:
Mol File:1835647-08-9.mol
N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide Structure
N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide Chemical Properties
Boiling point 342.0±42.0 °C(Predicted)
density 1.35±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka10.59±0.70(Predicted)
Safety Information
MSDS Information
N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide Usage And Synthesis
UsesPXT-012253 is a positron emission tomography (PET) ligand for mGluR4, as it binds to an allosteric site on mGluR4. PXT-012253 can be utilized in researches related to Parkinson's disease and levodopa-induced dyskinesia[1].
IC 50mGluR4
References[1] Takano A, et al. Characterization of [11C]PXT012253 as a PET Radioligand for mGlu4 Allosteric Modulators in Nonhuman Primates. Mol Imaging Biol. 2019 Jun;21(3):500-508. DOI:10.1007/s11307-018-1257-0
N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide Preparation Products And Raw materials
Tag:N-[4-Chloro-3-(methylthio)phenyl]-2-pyridinecarboxamide(1835647-08-9) Related Product Information
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