| Host | Mouse |
| Specificity | reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and NK cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells |
| Specificity | Reacts with the 24kD tetraspan CD81 molecule. |
| Specificity | Recognizes mouse CD83. |
| Immunogen | Human B cell line from Burkitt's lymphoma. |
| Conjugations | Biotin |
| Specificity | Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and non-killer cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells. |
| Conjugations | Phycoerythrin |
| Clone | Eat2 |
| Conjugations | FITC |
| Reactivity | Human |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Format | Biotin, Unmodified |
| Format | Phycoerythrin, Unmodified |
| Usage | Suitable for use in Flow Cytometry and Immunohistochemistry. Immunohistochemistry: Frozen sections. Flow Cytometry: 1:50. |
| Format | FITC, Unmodified |
| Immunogen | Mouse CD83. |
| Description | CD81 antibody is an FITC-conjugated mouse monoclonal antibody to mouse CD81. Validated for Flow. |
| Description | CD81 antibody is a PE-conjugated mouse monoclonal antibody to human CD81. Validated for Flow. |
| Description | CD83 antibody is a biotin-conjugated rat monoclonal antibody to mouse CD83. Validated for Flow. |
| Description | CD81 antibody is a biotin-conjugated mouse monoclonal antibody to mouse CD81. Validated for Flow. |
| Description | CD81 antibody is a PE-conjugated mouse monoclonal antibody to mouse CD81. Validated for Flow. |
| Application | FC |
| Target | CD83 |
| Target | CD81 |