| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
|
| | PD 140376 Basic information |
| Product Name: | PD 140376 | | Synonyms: | PD 140376;[3H]-PD 140376;Benzenebutanoic acid, 4-amino-β-[[(2R)-3-(1H-indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-, (βS)- | | CAS: | 149027-97-4 | | MF: | C33H40N4O5 | | MW: | 572.71 | | EINECS: | | | Product Categories: | | | Mol File: | 149027-97-4.mol |  |
| | PD 140376 Chemical Properties |
| Boiling point | 879.8±65.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | pka | 4.24±0.10(Predicted) |
| | PD 140376 Usage And Synthesis |
| Description | PD 140376 is a highly selective antagonist radioligand for the cholecystokinin(B)-gastrin receptor in guinea pig cerebral cortex & gastric mucosa in the central and peripheral nervous systems. | | Uses | PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with Ki values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively[1]. | | References | [1] J C Hunter, et al. [3H]PD 140376: a novel and highly selective antagonist radioligand for the cholecystokininB/gastrin receptor in guinea pig cerebral cortex and gastric mucosa. Mol Pharmacol. 1993 Apr;43(4):595-602 PMID:8474432 |
| | PD 140376 Preparation Products And Raw materials |
|