Anti-inflammatory agent 54

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Anti-inflammatory agent 54 Suppliers list
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: ATK CHEMICAL COMPANY LIMITED  
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Anti-inflammatory agent 54 manufacturers
Anti-inflammatory agent 54 Basic information
Product Name:Anti-inflammatory agent 54
Synonyms:Anti-inflammatory agent 54;2-Propenamide, 3-(2-furanyl)-N-[2-(6-methoxy-2-oxo-3(2H)-benzoxazolyl)ethyl]-, (2E)-
CAS:2924156-46-5
MF:C17H16N2O5
MW:328.32
EINECS:
Product Categories:
Mol File:2924156-46-5.mol
Anti-inflammatory agent 54 Structure
Anti-inflammatory agent 54 Chemical Properties
density 1.317±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka13.787±0.46(predicted)
Safety Information
MSDS Information
Anti-inflammatory agent 54 Usage And Synthesis
UsesAnti-inflammatory agent 54 (compound 9c) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC50: 2.4 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model[1].
References[1] Cui E, et al. Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents. J Nat Prod. 2023 Aug 25;86(8):1950-1959.. DOI:10.1021/acs.jnatprod.3c00309
Anti-inflammatory agent 54 Preparation Products And Raw materials
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