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| | 1,2-dihydrotanshinquinone Basic information |
| Product Name: | 1,2-dihydrotanshinquinone | | Synonyms: | 1,2-dihydrotanshinquinone;8,9-Dihydro-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione;Dihydrotanshiquinone;1,2-Di-hydrotanshinguinone;2-Dihydrotanshinquinone;Phenanthro[1,2-b]furan-10,11-dione, 8,9-dihydro-1,6-dimethyl-;1,2-Dihydrotanshinone I;1,2-Dihydrotanshinone | | CAS: | 77769-21-2 | | MF: | C18H14O3 | | MW: | 278.3 | | EINECS: | | | Product Categories: | | | Mol File: | 77769-21-2.mol |  |
| | 1,2-dihydrotanshinquinone Chemical Properties |
| Boiling point | 495.6±44.0 °C(Predicted) | | density | 1.286±0.06 g/cm3(Predicted) |
| | 1,2-dihydrotanshinquinone Usage And Synthesis |
| Uses | 1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1[1][2]. | | Cytotoxicity | IC50 (μg/mL): 5.6 (MIAPaCa-2) (Fronza etal. 2011) | | References | [1] Faleschini MT, et, al. Discovery of natural products potentially active against myotonic dystrophy type 1. Planta Med 2015; 81-YRW_03.
[2] Fronza M, et, al. In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica. Bioorg Med Chem. 2011 Aug 15;19(16):4876-81. DOI:10.1016/j.bmc.2011.06.067 |
| | 1,2-dihydrotanshinquinone Preparation Products And Raw materials |
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