chaetomellic acid A manufacturers
|
| | chaetomellic acid A Basic information |
| Product Name: | chaetomellic acid A | | Synonyms: | chaetomellic acid A;2-Butenedioic acid, 2-methyl-3-tetradecyl-, (2Z)-;Chaetomellic acid A, farnesyltransferase inhibitor | | CAS: | 148796-51-4 | | MF: | C19H34O4 | | MW: | 326.47 | | EINECS: | | | Product Categories: | | | Mol File: | 148796-51-4.mol |  |
| | chaetomellic acid A Chemical Properties |
| form | White to off-white solid. |
| | chaetomellic acid A Usage And Synthesis |
| Uses | Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice[1][2]. | | References | [1] Nogueira A, et al. The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction. Biomed Res Int. 2017;2017:5125980. DOI:10.1155/2017/5125980
[2] Lingham RB, et al. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protein transferase. Appl Microbiol Biotechnol. 1993 Nov;40(2-3):370-4. DOI:10.1007/BF00170395 |
| | chaetomellic acid A Preparation Products And Raw materials |
|