| Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
|
| Tel: |
0513-66337626 18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:Lepadin H
CAS:412328-25-7
Purity:98%HPLC Package:10mg，100mg，500mg，1g，2g，5g，10g，more
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Lepadin H
CAS:412328-25-7
Package:100mg/RMB 23500;25mg/RMB 13900;50mg/RMB 18300
|
Lepadin H manufacturers
- Lepadin H
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- $3400.00 / 100mg
-
2025-08-21
- CAS:412328-25-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Lepadin H Basic information |
| Product Name: | Lepadin H | | Synonyms: | Lepadin H;2,4-Octadienoic acid, (2S,3R,4aS,5S,8aR)-decahydro-5-[(5R)-5-hydroxyoctyl]-2-methyl-3-quinolinyl ester, (2E,4E)- | | CAS: | 412328-25-7 | | MF: | C26H45NO3 | | MW: | 419.64 | | EINECS: | | | Product Categories: | | | Mol File: | 412328-25-7.mol |  |
| | Lepadin H Chemical Properties |
| Boiling point | 528.415±25.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.011±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 15.258±0.20(predicted) |
| | Lepadin H Usage And Synthesis |
| Uses | Lepadin H is a marine alkaloid and ferroptosis inducer. Lepadin H exhibits significant cytotoxicity, promotes p53 expression, increases ROS production and lipid peroxidation, decreases SLC7A11 and GPX4 levels, and upregulates ACSL4 expression. Lepadin H induces ferroptosis through the p53-SLC7A11-GPX4 pathway[1]. | | References | [1] Wang W, et al. Marine Alkaloid Lepadins E and H Induce Ferroptosis for Cancer Chemotherapy. J Med Chem. 2023 Aug 24;66(16):11201-11215. DOI:10.1021/acs.jmedchem.3c00659 |
| | Lepadin H Preparation Products And Raw materials |
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