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| | 4-Chlorobenzyl chloride Basic information |
| | 4-Chlorobenzyl chloride Chemical Properties |
| Melting point | 27-29 °C (lit.) | | Boiling point | 216-222 °C (lit.) | | density | 1.26 | | Fp | 208 °F | | refractive index | 1.5575 | | storage temp. | Store at RT. | | solubility | insoluble | | form | Crystalline Low Melting Solid | | color | Colorless to white | | Specific Gravity | 1.26 | | Water Solubility | insoluble | | Sensitive | Lachrymatory | | BRN | 471558 | | Stability: | Moisture Sensitive | | Major Application | environmental
pharmaceutical | | InChI | 1S/C7H6Cl2/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2 | | InChIKey | JQZAEUFPPSRDOP-UHFFFAOYSA-N | | SMILES | ClCc1ccc(Cl)cc1 | | CAS DataBase Reference | 104-83-6(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 1-chloro-4-(chloromethyl)-(104-83-6) | | EPA Substance Registry System | 4-Chlorobenzyl chloride (104-83-6) |
| Hazard Codes | C,N,Xn | | Risk Statements | 34-51/53-20/21/22-52/53-43-22 | | Safety Statements | 26-36/37/39-45-29-61-36/37 | | RIDADR | UN 3427 6.1/PG 3 | | WGK Germany | 2 | | RTECS | XT0720000 | | F | 19-21 | | Hazard Note | Corrosive/Lachrymatory | | TSCA | TSCA listed | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29049090 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 2
Skin Sens. 1 | | Hazardous Substances Data | 104-83-6(Hazardous Substances Data) |
| | 4-Chlorobenzyl chloride Usage And Synthesis |
| Chemical Properties | Colorless to light yellow liqui | | Uses | Reagent used in derivatization of, for example, a calix[4]arene1 and a tryptamine.2 | | Uses | 4-Chlorobenzyl Chloride is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents. | | Uses | 4-Chlorobenzyl chloride was the test compound for determining rat hepatocellular thiols by HPLC. As a reagent used in derivatization of, for example, a calix[4]arene and a tryptamine. It is widely used as an intermediate for manufacturing organic compounds like benzyl alcohol and benzyl cyanide. Also used in fuel as a gum inhibitor. | | General Description | 4-Chlorobenzyl chloride is generally used in the preparation of quaternary ammonium salts. It acts as an intermediate in the production of rice herbicide, pharmaceuticals and pesticides. | | Hazard | Irritating to skin, eyes. | | Purification Methods | Dry it over CaSO4, then fractionally distil it under reduced pressure. Crystallise it from heptane or dry diethyl ether at low temperature. [Beilstein 5 IV 816.] LACHRYMATORY. |
| | 4-Chlorobenzyl chloride Preparation Products And Raw materials |
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