Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:Antitumor agent-49 CAS:2763914-21-0 Package:50mg;5mg
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| Antitumor agent-49 Basic information |
Product Name: | Antitumor agent-49 | Synonyms: | Antitumor agent-49;9H-Pyrido[3,4-b]indolium, 1-methyl-7-[2-[4-[[5-oxido-4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]oxy]butoxy]-2-oxoethoxy]-2-(phenylmethyl)-9-(3-phenylpropyl)-, bromide (1:1) | CAS: | 2763914-21-0 | MF: | C42H41N4O8S.Br | MW: | 841.77 | EINECS: | | Product Categories: | | Mol File: | 2763914-21-0.mol |  |
| Antitumor agent-49 Chemical Properties |
| Antitumor agent-49 Usage And Synthesis |
Uses | Antitumor agent-49 (Compound 10) is a Harmine derivative-furoxan hybrids containing NO donor, with antitumor activities. Antitumor agent-49 shows cytotoxic activity against HepG2 cells with an IC50 of 1.79?μM. Antitumor agent-49 produces high levels of NO in vitro[1]. | References | [1] Zhezhe Li, et al. Synthesis of harmine-nitric oxide donor derivatives as potential antitumor agents. Bioorg Med Chem Lett. 2022 Mar 24;65:128698. DOI:10.1016/j.bmcl.2022.128698 |
| Antitumor agent-49 Preparation Products And Raw materials |
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