1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl-

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1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl- Basic information
Product Name:1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl-
Synonyms:1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl-;TLR4-IN-1
CAS:2617578-93-3
MF:C10H12O4
MW:196.2
EINECS:
Product Categories:
Mol File:2617578-93-3.mol
1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl- Structure
1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl- Chemical Properties
Boiling point 336.3±32.0 °C(predicted)
density 1.203±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka5.75±0.40(predicted)
Safety Information
MSDS Information
1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl- Usage And Synthesis
UsesTLR4-IN-1 (compound 3k) inhibits the cell viability of RAW264.7 with an IC50 of 1.02 μM. TLR4-IN-1 inhibits the release of cytokine TNF-α, IL-1β and IL-6, and exhibits anti-inflammatory efficacy in rats rheumatoid arthritis models[1].
References[1] Zhou S, et al., Design, Synthesis, and Antirheumatoid Arthritis Mechanism of TLR4 Inhibitors. ACS Omega. 2024 Aug 14;9(34):36232-36241. DOI:10.1021/acsomega.4c02344
1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl- Preparation Products And Raw materials
Tag:1,2-Cyclopentanedione, 3-(1,3-dioxobutyl)-5-methyl-(2617578-93-3) Related Product Information
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