L-xylulose

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Products Intro: Product Name:L-Xylulose
CAS:527-50-4
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Products Intro: Product Name:L-xylulose
CAS:527-50-4
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Products Intro: Product Name: L-XYLULOSE
CAS:527-50-4
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Products Intro: Product Name:L-xylulose
CAS:527-50-4
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Products Intro: Product Name:L-Xylulose
CAS:527-50-4
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  • L-Xylulose
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L-xylulose Basic information
Product Name:L-xylulose
Synonyms:L-XYLULOSE;L-THREO-PENTULOSE;threo-2-Pentulose, L-threo-Pentulose;L-Xylulose ,98%;L-Xylulose - Aqueous solution;L-threo-2-Pentulose (9CI);threo-2-pentulose;(3R,4S)-2-(hydroxymethyl)oxolane-2,3,4-triol
CAS:527-50-4
MF:C5H10O5
MW:150.13
EINECS:
Product Categories:CARBOHYDRATE
Mol File:527-50-4.mol
L-xylulose Structure
L-xylulose Chemical Properties
Melting point Not Applicable
Boiling point 469.1±45.0 °C(Predicted)
density 1.516±0.06 g/cm3(Predicted)
Fp >230 °F
storage temp. 2-8°C
solubility Methanol (Slightly), Water (Soluble)
form syrup
pka11.90±0.20(Predicted)
color light yellow
Optical Rotation+33
LogP-1.200 (est)
Safety Information
WGK Germany 3
HS Code 29400090
MSDS Information
ProviderLanguage
SigmaAldrich English
L-xylulose Usage And Synthesis
Chemical PropertiesL-xylulose is a clear liquid. It is a ketopentose, meaning that it has five carbon atoms and a ketogroup at carbon C-2. It has a molecular formula of C5H10O5 and a molar mass of 150.13 g/mol. Xylulose is almost colorless and it forms syrup. The formation of crystals has not been reported (Budavari, 1996). Both D- and L - enantiomers of xylulose are found as intermediates in metabolic pathways of prokaryotes as well as eukaryotes. Both forms are rare in nature (Doten and Mortlock, 1985b).
UsesL-Xylulose is used in studies relating to potential inhibitors of glycosidases and has been proven to inhibit oligosaccharide processing to a degree.
DefinitionChEBI: L-xylulose is a xylulose. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an enantiomer of a D-xylulose.
ApplicationL-Xylulose has been shown to be a specific inhibitor of certain α-glucosidases,while having virtually no effect on other glycosidases such as β-glucosidase or α- and β-mannosidases. Furthermore,it is a specific inhibitor of the N-linked glycoproteinprocessing enzyme,glucosidase I, but does not inhibit glucosidase I or otherglycoprotein processing mannosidases. Thus it could prove to be a useful inhibitor forstudying glycoprotein processing, especially as it has been proven to be non-toxic andto also be effective in cell cultures (Muniruzzaman et al., 1996). L-Xylulose has been shown to have a strong inhibitory effect on the a-glucosidases,sucrase and maltase, present in the small intestine. Thus, an L-xylulose containing drug preparation for reducing blood sugar levels in humans and animals has been patented (Heinz et al.,1998).
PreparationIn 1933 a synthetic procedure for producing small amounts of D- and L -xylulose was introduced. In this method D- or L-xylose is epimerized to the corresponding diastereomer. The isomerization of xylose in pyridine leads to the production of xylulose (Touster, 1962). This enzyme catalyzes the production of L-xylulose from xylitol using either PQQ (pyrroloquinoline quinone) or FAD (flavin adenine dinucleotide) as prosthetic group, and L-xylulose is accumulated in the medium (Adachi et al., 1999; Adachi et al., 2001).
L-xylulose Preparation Products And Raw materials
Tag:L-xylulose(527-50-4) Related Product Information
9H-Xanthen-9-one, 2-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-1,3,6,7-tetrahydroxy- 2-Deoxy-D-xylose Xanthone Impurity 9 4-[(1R)-1,5-Dimethyl-4-hexen-1-yl]-6-hydroxy-2-cycloehexen-1-one Benzene, 4-[(1S)-1,5-dimethyl-4-hexen-1-yl]-2-methoxy-1-methyl- 7-ACETYLLYCOPSAMINE XANTHORRHIZOL 5H-Furo[3,2-b]xanthene-2-carboxylic acid, 2,3-dihydro-11-methyl-5-oxo- 5-[(1R)-1,5-Dimethyl-4-hexen-1-yl]-2-methyl-3-cyclohexene-1,1-diol 4-[(1R)-1,5-Dimethyl-4-hexen-1-yl]-2-cyclohexen-1-one [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-(3,4,5-trihydroxyoxan-2-yl)oxy-phosphoryl]oxy-phosphinic acid 3-Morpholinopropanol D-[2-2H]XYLOSE Xanthone Impurity 11 Xanthophyll 1H-Benzimidazole, 1-(1-oxo-2-propenyl)-2-(4-thiazolyl)- D-Xylose, 5-deoxy- D-(+)-MELEZITOSE

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