| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:EGR-1-IN-2 CAS:152367-54-9 Package:50mg/RMB 13800
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| | 2-Naphthalenol, 1-[4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl]- Basic information |
| | 2-Naphthalenol, 1-[4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl]- Chemical Properties |
| Boiling point | 529.0±60.0 °C(predicted) | | density | 1.25±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 8.32±0.50(predicted) |
| | 2-Naphthalenol, 1-[4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl]- Usage And Synthesis |
| Uses | EGR-1-IN-2 (compound 2) is an EGR-1 inhibitor with anti-inflammatory activity. EGR-1-IN-2 inhibits the formation of EGR-1-DNA complexes induced by TNF-α in HaCaT cells[1]. | | References | [1] Yoon H, et al. Pyrazolines inhibiting the activity of the early growth response-1 DNA-binding domain[J]. Bioorganic & Medicinal Chemistry Letters, 2024: 129952. DOI:10.1016/j.bmcl.2024.129952 |
| | 2-Naphthalenol, 1-[4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl]- Preparation Products And Raw materials |
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