KRAS inhibitor-26

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KRAS inhibitor-26 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
KRAS inhibitor-26 Basic information
Product Name:KRAS inhibitor-26
Synonyms:KRAS inhibitor-26
CAS:3030576-80-5
MF:
MW:676.73
EINECS:
Product Categories:
Mol File:3030576-80-5.mol
KRAS inhibitor-26 Structure
KRAS inhibitor-26 Chemical Properties
density 1.450±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
Safety Information
MSDS Information
KRAS inhibitor-26 Usage And Synthesis
UsesKRAS inhibitor-26 (compound 194a) is a potent KRAS G12V inhibitor (IC50: ≤100 nM). KRAS inhibitor-26 can be used for cancer research[1].
IC 50KRas G12V: <100 nM (IC50)
References[1] James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. Patent. WO 2024/040131 A1.
KRAS inhibitor-26 Preparation Products And Raw materials
Tag:KRAS inhibitor-26(3030576-80-5) Related Product Information
2-Propen-1-one, 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]- 2,7-Diazaspiro[4.4]nonane-2-acetamide, α-cyclopentyl-7-[[(2R,3R)-3-cyclopropyl-1-methyl-2-aziridinyl]carbonyl]-N-[(1R,10S,12S,18S)-1-[5-(4-cyclopropyl-1-piperazinyl)-2-[(1S)-1-methoxyethyl]-3-pyridinyl]-2,7,8,10,11,12,13,16,17,18,19,21,22,23-tetradecahydro-22,22-dimethyl-13,19-dioxo-2-(2,2,2-trifluoroethyl)-15H-3,5-etheno-14,18-imino-6,10-methano-6H-pyrrolo[3,4-g][1,12,4,18]dioxadiazacyclodocosin-12-yl]-, (αS,5S)- NAV2729 RMC6291 RMC-7977 EHT1864