| Company Name: |
Wuxi AppTec |
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022-59987777 13552403979 |
| Email: |
jia_guoqiang@wuxiapptec.com |
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| | 6H-Thieno[2,3-b]pyrrole-5-carboxylic acid Basic information |
| | 6H-Thieno[2,3-b]pyrrole-5-carboxylic acid Chemical Properties |
| Melting point | 207 °C (decomp) | | Boiling point | 437.4±25.0 °C(Predicted) | | density | 1.609±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Solid | | pka | 4.37±0.30(Predicted) | | color | Light brown to brown |
| | 6H-Thieno[2,3-b]pyrrole-5-carboxylic acid Usage And Synthesis |
| Uses | DAO-IN-1 is a potent inhibitor of D-amino acid oxidase (DAO) with an IC50 value of 269 nM. DAO is an enzyme responsible for D-serine metabolism, D-serine is a co-agonist of NMDA receptors[1]. | | References | [1] Sparey T, et al. The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3386-91. DOI:10.1016/j.bmcl.2008.04.020 |
| | 6H-Thieno[2,3-b]pyrrole-5-carboxylic acid Preparation Products And Raw materials |
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