| Company Name: |
BePharm Ltd |
| Tel: |
400-685-9117 |
| Email: |
market@bepharm.com |
| Company Name: |
Energy Chemical |
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
|
| | 1-(2-hydroxy-5-nitrophenyl)propan-1-one Basic information |
| | 1-(2-hydroxy-5-nitrophenyl)propan-1-one Chemical Properties |
| Melting point | 93-94 °C | | Boiling point | 299.3±25.0 °C(Predicted) | | density | 1.321±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | pka | 5.45±0.30(Predicted) |
| | 1-(2-hydroxy-5-nitrophenyl)propan-1-one Usage And Synthesis |
| Preparation | Preparation by Friedel–Crafts acylation of p-nitrophe-nol with propionyl chloride in nitrobenzene in the presence of aluminium chloride (36%)
Also obtained by Fries rearrangement of p-nitrophenyl propionate (m.p. 63–64°) in nitrobenzene in the presence of aluminium chloride at 125° for 5 h (23%)
Preparation by reaction of boron trichloride with 2-methoxy-5-nitropropiophe-none in methylene chloride, first at 78°, then at r.t. for 14 h (92%). Also obtained by nitration of o-hydroxypropiophenone (23%), in acetic acid with fuming nitric acid, first at 0°, then at 60°
Also obtained by alkaline hydrolysis of 3-methyl-6-nitrochromone (m.p. 147–148°) (85%). |
| | 1-(2-hydroxy-5-nitrophenyl)propan-1-one Preparation Products And Raw materials |
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