4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE manufacturers
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| | 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Basic information |
| Product Name: | 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE | | Synonyms: | 4-epianhydrotetracyclinehydrochloride’canbeusedassecondarystandard’;4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE;Lymecycline Impurity 4（Lymecycline EP Impurity D）;Tetracycline EP Impurity D HCl;(4R,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE;4-Epianhydrotetracycline hydrochloride, 'can be used as a secondary standard', 97%;4-Epianhydroustetracycline hydrochloride;4-Epianhydrotetracycline hydrochloride,97%,'can be used as a secondary standard' | | CAS: | 4465-65-0 | | MF: | C22H23ClN2O7 | | MW: | 462.88 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 4465-65-0.mol |  |
| | 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties |
| Melting point | 220 °C | | storage temp. | -20°C Freezer | | solubility | DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml | | form | Powder | | color | Orange | | BRN | 3840711 | | Major Application | clinical testing | | InChIKey | XBSQEFHDCDFNJU-PFRKANOHNA-N | | SMILES | O[C@@]12C(C(C(=O)N)=C(O)[C@H](N(C)C)[C@]1([H])CC1C(=C3C=CC=C(O)C3=C(O)C=1C2=O)C)=O.Cl |&1:1,9,13,r| | | EPA Substance Registry System | 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0) |
| Hazard Codes | Xn | | Risk Statements | 63-36-22 | | Safety Statements | 36/37/39-26 | | WGK Germany | 3 | | HS Code | 29413000 | | Storage Class | 11 - Combustible Solids |
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ACROS
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| | 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | orange powder | | Uses | An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study. | | Uses | Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity. |
| | 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Preparation Products And Raw materials |
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