| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
|
| | ANTI-FERRITIN Basic information |
| | ANTI-FERRITIN Chemical Properties |
| storage temp. | −20°C | | form | liquid | | biological source | rabbit |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 | | Storage Class | 12 - Non Combustible Liquids |
| | ANTI-FERRITIN Usage And Synthesis |
| Uses | Anti-Ferritin, Human antibody is suitable for use in Ouchterlony double diffusion (1:16 using human spleen ferritin), and immunoelectrophoresis. The antibody may also be used in western blot (1:1000 using frozen liver homogenates) and immunoprecipitation (using 300 μg of cell lysate incubated with 6 mul of anti-ferritin for 1h at 4 ° C). | | General Description | Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron andferritinare distributed relatively same in the eye. Ferritin is made up of heavy and light chains. | | Biochem/physiol Actions | Ferritin is an iron-storage protein that regulates iron-homeostasis in cells. While mitochondrial ferritin is a homopolymer, the cytosolic form consists of heteropolymeric L- and H-chains. Genetic mutations in ferritin L-chains have been associated with neurodegenerative disorders, whereas altered levels of ferritin have been linked to hemophagocytic lymphohistiocytosis and adult-onset Still′s disease . In immunoelectrophoresis, anti-ferritin, human antibody is specific for ferritin when used against human spleen extract and purified ferritin. No reactivity is observed against normal human serum. |
| | ANTI-FERRITIN Preparation Products And Raw materials |
|