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| | Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) Basic information |
| Product Name: | Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) | | Synonyms: | Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1)/4-(1-Aminocyclopropyl)benzoic acid methyl ester hydrochloride;Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride;Methyl 4-(1-aminocyclopropyl);Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1);Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, HCl (1:1) | | CAS: | 1014645-87-4 | | MF: | C11H14ClNO2 | | MW: | 227.69 | | EINECS: | | | Product Categories: | | | Mol File: | 1014645-87-4.mol |  |
| | Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) Chemical Properties |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | Appearance | Off-white to light brown Solid |
| | Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) Usage And Synthesis |
| Synthesis | Step 2: Methyl 4-(1-aminocyclopropyl)benzoate (1.63 g, 8.5 mmol) was dissolved in ethyl acetate (10 mL), and 2.0 M ether solution of hydrogen chloride (6.0 mL, 12 mmol) was slowly added. The reaction mixture was stirred at room temperature for several minutes and then concentrated under reduced pressure to remove the solvent to give methyl 4-(1-aminocyclopropyl)benzoate hydrochloride as a light brown solid in quantitative yield. | | References | [1] Patent: WO2012/39972, 2012, A1. Location in patent: Page/Page column 39
[2] Journal of Organic Chemistry, 2010, vol. 75, # 12, p. 4078 - 4085
[3] Patent: WO2012/76063, 2012, A1. Location in patent: Page/Page column 39
[4] Patent: US2013/261100, 2013, A1. Location in patent: Paragraph 0273-0274; 02796 |
| | Benzoic acid, 4-(1-aminocyclopropyl)-, methyl ester, hydrochloride (1:1) Preparation Products And Raw materials |
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