- Cyclopentadecanolide
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- $0.00 / 1KG
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2025-09-15
- CAS:106-02-5
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- ω-Pentadecalactone
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- $29.00 / 1g
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2025-09-12
- CAS:106-02-5
- Min. Order:
- Purity: 95.00%
- Supply Ability: 10g
- Cyclopentadecanolide
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- $0.00 / 25KG
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2025-08-08
- CAS:106-02-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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| | Cyclopentadecanolide Basic information |
| | Cyclopentadecanolide Chemical Properties |
| Melting point | 34-38 °C(lit.) | | Boiling point | 137 °C2 mm Hg(lit.) | | density | 0.918 g/mL at 25 °C(lit.) | | vapor pressure | 0.085Pa at 25℃ | | FEMA | 2840 | OMEGA-PENTADECALACTONE | | refractive index | 1.4700 | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform, Ethyl Acetate, Methanol (Slightly) | | form | Solid | | color | White to Off-White | | Odor | at 10.00 % in dipropylene glycol. musk animal powdery natural fruity | | Odor Type | musk | | biological source | synthetic | | Water Solubility | Soluble in alcohol, dipropylene glycol. Insoluble in water. | | Merck | 14,3910 | | JECFA Number | 239 | | BRN | 143710 | | LogP | 5.79 at 25℃ | | CAS DataBase Reference | 106-02-5(CAS DataBase Reference) | | NIST Chemistry Reference | Oxacyclohexadecan-2-one(106-02-5) | | EPA Substance Registry System | Oxacyclohexadecan-2-one (106-02-5) |
| Safety Statements | 24/25 | | WGK Germany | 1 | | RTECS | RN9775000 | | TSCA | Yes | | HS Code | 29322090 | | toxicity | Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg (Levenstein, 1974). |
| | Cyclopentadecanolide Usage And Synthesis |
| Chemical Properties | Cyclopentadecanolide is a white crystalline low melting solid. melting at
36-37℃. to a colorless, viscous oil. B.P. 280℃. Delicately animal, musky and sweet, extremely tenacious odor of outstanding uniformity. Common use level in the perfume oil is
about 0.1 to 0.4%. | | Chemical Properties | Cyclopentadecanolide occurs in small quantities in,
for example, angelica root oil. It forms colorless crystals (mp 37–38°C) with a
delicate, musk-like odor. | | Chemical Properties | ω-Pentadecalactone has an extraordinarily persistent, musk-like odor. | | Occurrence | Originally reported found in the essential oil from angelica roots. | | Uses | As a fixative in perfumery. | | Uses | Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen. | | Uses | Pentadecanolide may be used for the synthesis of poly(pentadecanolide) (PPDL) by Novozyme 435 catalyzed ring-opening polymerization. It may be employed as starting reagent for the synthesis of terminally-branched iso-fatty acids (iso-C15-C17). | | Definition | ChEBI: Cyclopentadecanolide is a macrolide. | | Application | Cyclopentadecanolide gives highly interesting effects when applied to certain flavors,
e. g. alcoholic beverages, dentifrice flavors etc.
There is very often a unanimous preference
for the flavor that is properly treated with the
hctone. Concentration in such flavors may be about
0.02 to 1.50 ppm calculated upon the finished
consumer product. However, it should be
kept in mind, that dentifrices are flavored at
extremely high concentration (about 100) and
it may therefore ghe an underestimated evaluation of the power of this Lactone, The most
frequent abuse of Cyclopentadecanolide is
that of over-dosage. It is also used extensively in Berry flavors, Liquor, Wine, Brandy, Fruit, Nut, Vanilla copositions, etc. | | Preparation | The main industrial syntheses start from compounds produced
from cyclododecatriene: either by ring expansion of cyclododecanone or
by depolymerization of polyesters of 15-hydroxypentadecanoic acid (from
1,12-dodecanediol). | | Aroma threshold values | Detection: 1 to 4 ppb | | Taste threshold values | Taste characteristics at 75 ppm: vanilla bean, powdery helioropine, creamy and licorice. | | Synthesis Reference(s) | Tetrahedron Letters, 34, p. 6107, 1993 DOI: 10.1016/S0040-4039(00)61741-0
The Journal of Organic Chemistry, 50, p. 2394, 1985 DOI: 10.1021/jo00213a044 | | General Description | Pentadecanolide is one of the major components, isolated from the root of Angelica archangelica L., species. It is a synthetic musk, which exists as a widespread contaminant in the environment. | | Flammability and Explosibility | Non flammable | | Trade name | Macrolide® (Symrise), Exaltolide®, Exaltolide®Total (Firmenich),
Pentalide (Soda Aromatic). | | Purification Methods | It has been recrystallised from MeOH (4 parts) at -15o. [Hundieck |
| | Cyclopentadecanolide Preparation Products And Raw materials |
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