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4-Hydroxy-3-methoxymandelic acid

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Products Intro: Product Name:4-Hydroxy-3-methoxymandelic acid
CAS:55-10-7
Purity:99% Package:1KG;0.00;USD|25KG;0.00;USD|100KG;0.00;USD
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Products Intro: Product Name:4-Hydroxy-3-methoxymandelic acid
CAS:55-10-7
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Products Intro: Product Name:DL-4-Hydroxy-3-methoxymandelic acid
CAS:55-10-7
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Products Intro: Product Name:Vanillylmandelic acid
CAS:55-10-7
Purity:97.13% Package:100mg;48USD|200mg;69USD|50mg;33USD Remarks:REAGENT;FOR LABORATORY USE ONLY
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CAS:55-10-7

4-Hydroxy-3-methoxymandelic acid manufacturers

4-Hydroxy-3-methoxymandelic acid Basic information
Product Name:4-Hydroxy-3-methoxymandelic acid
Synonyms:alpha,4-dihydroxy-3-methoxy-benzeneaceticaci;HYDROXY-3-METHOXYMANDELIC ACID, D,L-4-;DL-4-HYDROXY-3-METHOXYMANDELIC ACID;DL-3-METHOXY-4-HYDROXYMANDELIC ACID;DL-VANILLOMANDELIC ACID;ALPHA,4-DIHYDROXY-3-METHOXYBENZENEACETIC ACID;VANILMANDELIC ACID;VANILLYLMANDELIC ACID
CAS:55-10-7
MF:C9H10O5
MW:198.17
EINECS:200-224-0
Product Categories:Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics Compounds;Aromatics
Mol File:55-10-7.mol
4-Hydroxy-3-methoxymandelic acid Structure
4-Hydroxy-3-methoxymandelic acid Chemical Properties
Melting point 132-134 °C (dec.)(lit.)
Boiling point 255.48°C (rough estimate)
density 1.2539 (rough estimate)
FEMA 4660 | HYDROXY(4-HYDROXY-3-METHOXYPHENYL)ACETIC ACID
refractive index 1.4570 (estimate)
storage temp. 2-8°C
solubility H2O: ~50 mg/mL
pka3.42±0.10(Predicted)
form powder
color white to off-white
Water Solubility freely soluble
JECFA Number2020
Merck 14,9933
BRN 2213227
Major Applicationclinical testing
InChI1S/C9H10O5/c1-14-7-4-5(2-3-6(7)10)8(11)9(12)13/h2-4,8,10-11H,1H3,(H,12,13)
InChIKeyCGQCWMIAEPEHNQ-UHFFFAOYSA-N
SMILESOC1=C(OC)C=C(C(O)C(O)=O)C=C1
LogP-0.212 (est)
EPA Substance Registry SystemBenzeneacetic acid, .alpha.,4-dihydroxy-3-methoxy- (55-10-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
10-23
TSCA TSCA listed
HS Code 29181998
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
4-Hydroxy-3-methoxymandelic acid Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesA metabolite of catecholamines.
DefinitionChEBI: An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.
Biochem/physiol ActionsEpinephrine and norepineprine metabolite.
in vivo

Vanillylmandelic acid (intra-arterial injection over 1 min; 1, 10 and 100 mg/kg; the 60 min-observation period) produces a significant difference between vanillylmandelic acid groups and controls. Vanillylmandelic acid decreases the heart rate by 17.5%, 17.9% and 18.9% after 1, 10 and 100 mg/kg, respectively. Mean blood pressure is decreased by 13.5% in control animals as compared to 37%, 23% and 26% after 1, 10 and 100 mg/kg, respectively, in wistar rats[1].

IC 50Human Endogenous Metabolite; Microbial Metabolite
4-Hydroxy-3-methoxymandelic acid Preparation Products And Raw materials
Raw materials2-METHOXYCYCLOHEXANOL 98% MIXTURE OF-->SODIUM GLYOXYLATE-->VanillylMandelic Acid Ethyl Ester-->Sodium oxalate-->Cyclohexene-->Guaiacol-->Glyoxylic acid-->Vanillin-->Chloroform
Preparation ProductsETHYL HOMOVANILLATE
Tag:4-Hydroxy-3-methoxymandelic acid(55-10-7) Related Product Information
DL-Mandelic acid Hyaluronic acid Malic acid Mandelic acid 4-Chloromandelic acid CHLOROPHOSPHONAZO III Ethyl 2-(Chlorosulfonyl)acetate Folic acid (Trifluoromethoxy)benzene (+/-)-VANILMANDELIC-D3 ACID DL-4-HYDROXY-3-METHOXYMANDELIC-2-D1 ACID Vanilmandelic-[13C,d3] Acid 4-Hydroxyphenylacetic acid (S)-(+)-Mandelic acid Anisole Citric acid Ascoric Acid DL-4-HYDROXY-3-METHOXYMANDELIC ACID

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